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Dangerous elevations in blood pressure may occur if tca are combined with clonidine catapres catapres tts. In summary tricyclic antidepressants can act through nmda antagonism opioidergic effects sodium potassium and calcium channel blocking through interfering with the reuptake of serotonin and a…

Cyclic antidepressants ease depression by affecting chemical messengers neurotransmitters used to communicate between brain cells. By inhibiting their reuptake more serotonin and norepinephrine lingers within the synaptic cleft available to bind to postsynaptic receptors and trigger their neuronal…