What Is An Example Of A Spontaneous Mutation
The c is converted to u and mec to 5 meu thymine fig. Spontaneous mutations are alleles of initially unknown genes and are given allele names and symbols based on their phenotype e g.
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Our ability to distinguish red and green is the result of first a duplication event accidental copying of a stretch of dna that happened to include one of our color detecting genes followed by 3 mutations that lead one of the copies to differ from the other.
What is an example of a spontaneous mutation. Both mec and c occasionally loose an amino group. Genetic mutation is a permanent change in a sequence of a gene that causes it to differ significantly from the. Large gene provide a large target and tend to mutate more frequently.
Spontaneous deamination of 5 methyl cytosine. Blue eyes are the result of a spontaneous mutation. A study of the five coat color loci in mice showed that the rate of mutation ranged from 2 x 10 6 to 40 x 10 6 mutations per gamete per gene.
One example of spontaneous mutation is the appearance of sickle cell anemia in humans. A naturally occurring mutation in the absence of a mutagen that would otherwise be a known factor for inducing a particular mutation. What are some examples of spontaneous genetic mutation.
Induced mutations occur due to the incorporation of base analogs base mispairing and base damage while spontaneous mutations occur due to the errors in dna replication spontaneous lesions like depurination and deamination and transposable genetic elements. Another source of spontaneous mutation is a change in 5 methyl cytosine 5 mec a methyl form of cystoine. It occurs naturally and it has stuck around for new generations because it is beneficial to carry the sickle.
The spontaneous mutation rate varies.
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